Molecular genetics of enterobacteria and their viruses. Isolation of mutants; genetic exchange and mapping; complementation; suppression; transposons; gene expression and regulation; and genomics. Examples illustrate applications to molecular cloning of recombinant DNA, and to the study of bacterial pathogenesis.

Prerequisite: Biological Sciences 101, 102, Biological Sciences 103 or course 140; course 102 recommended (may be taken concurrently).