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Coaker, Gitta L. Assistant Professor of Plant Pathology Department of Plant
Pathology |
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| Degree | Institution | Year | Specialization | |||
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| B.S. | University of Arizona | 1998 | Ecology and Evolutionary Biology | |||
| Ph.D. | Ohio State University | 2003 | Genetics and Plant Pathology | |||
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| Area of Specialization | ||||||
| Molecular biology, genetics and proteomics of plant-microbe interactions; plant bacteriology. | ||||||
| Research Statement | ||||||
| Research in the Coaker laboratory focuses on the molecular genetics of plant innate immunity. We use a combination of molecular biology, genetics, biochemistry and high-throughput proteomics to elucidate the signaling mechanisms associated with plant disease resistance following pathogen perception. We are currently using the Arabidopsis-Pseudomonas syringae model system to (1) investigate the host targets and activation mechanisms of bacterial effectors and (2) decipher the early signaling events that occur during plant resistance gene activation. | ||||||
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Selected
Publications
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Coaker G., G. Zhu, Z. Ding, S.R. Van Doren, and B. J. Staskawicz. 2006. Eukaryotic cyclophilin acts as a molecular switch for bacterial effector activation. Molecular Microbiology 61(6): 1485-1496.
Chisholm S.*, G. Coaker*, B. Day*, and B. J. Staskawicz. 2006. Host-microbe interactions: shaping the evolution of the plant immune response. Cell 124(4): 803-814. * These authors contributed equally to this work. Coaker G., A. Falick, and B. J. Staskawicz. 2005. Activation of a phytopathogenic bacterial effector protein by a eukaryotic cylophilin. Science 308(5721): 548-550. Coaker G., B. Willard, M. Kinter, E. J. Stockinger, and D. Francis. 2004. Proteomic analysis of resistance to bacterial canker of tomato. Molecular Plant Microbe Interactions 17(9): 1019-1028. Coaker G., and D. Francis. 2004. Mapping, genetic effects, and epistatic interaction of two bacterial canker resistance QTLs from Lycopersicon hirsutum. Theoretical and Applied Genetics 108: 1047-1055. Coaker G., and D. Francis. 2004. Measuring the effect of quantitative trait loci on vascular morphology and development in the tomato stem. Acta Horticulturae (ISHS) 637: 309-316. Qu S., G. Coaker, D. Francis, B. Zhou, and G.-L. Wang. 2003. Development of a new transformation-competent artificial chromosome (TAC) vector and construction of tomato and rice TAC libraries. Molecular Breeding 12: 297-308. Coaker G., T. Meulia, E. Kabelka, A. Jones, and D. Francis. 2002. A quantitative trait locus controlling aspects of stem morphology and vascular development in Lycopersicon esculentum X Lycopersicon hirsutum crosses is located on chromosome 2. The American Journal of Botany 89(12): 1859-1866. PUBLICATION REVIEWS - PERSPECTIVES SECTION IN SCIENCE Schulze-Lefert P., and B. Stephane. 2005. Plant sciences: recognition at a distance. Science 308(5721):506-508. | ||||||